Psychedelics

Episode 72: When The Trip Doesn’t End with Ed Prideaux

May 28, 2022 Narcotica Episodes, Psychedelics 01:17:41 0 Comments

Psychedelics and other drugs can trigger a condition called Hallucinogen Persisting Perception Disorder, a terrible name for a real condition that we don’t have much data on and is poorly understood. But while it’s clear that psychedelics shouldn’t be illegal, it’s also clear we’re still learning about some of the risks. This fascinating and often distressing phenomenon deserves a closer look, but not everything about it is devastatingly tragic, either.

In this episode of Narcotica, co-host Troy Farah talks all about HPPD with Ed Prideaux, a master’s student in psychology at the University of East London with a background in journalism. Ed is currently focused on researching and addressing the problems, possibilities and questions raised by HPPD: a broad, under-researched and not entirely uncommon condition in which people experience sustained and distressing changes to their visual perception (among other effects) after psychedelic trips. Ed has lived with these visual effects for nearly seven years, and is affiliated with a nonprofit launched last year to promote harm reduction around HPPD called the Perception Restoration Foundation.

Follow Ed at https://edprideaux.journoportfolio.com/
Visit the Perception Restoration Foundation at: Perception.Foundation

Some more info on perception as a hallucination: https://www.newstatesman.com/science-tech/2022/02/is-reality-a-hallucination-the-neuroscientist-anil-seth-thinks-so

Some of the studies mentioned in this episode:
The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act
https://pubmed.ncbi.nlm.nih.gov/29753748/
Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants
https://pubmed.ncbi.nlm.nih.gov/35076721/
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science
https://doi.org/10.1177%2F02698811211069100

If you liked this episode, here are others you might enjoy:
Episode 57: Autism, Acid and the Altered Brain with Aaron Orsini and Justine Lee
Episode 64: LSD And Psilocybin For Physical Pain? with Greg McKee and Dr. Johannes Ramaekers
Episode 59: Psychedelic Extinction—How Poaching Endangers Some Psychoactive Plants with Dr. Anya Ermakova

Follow Narcotica on Instagram, Facebook, Twitter, YouTube and support us on Patreon. We just opened a shop where you can order Narcotica merch: narcocast.myshopify.com Help keep this podcast ad-free! Your support is appreciated! We’re on Spotify, iTunes, Stitcher and more. Tell your friends about us! Rate us! And thanks for your support!

*Note: Troy says niacin is Vitamin C, it’s actually Vitamin B3. We regret the error.

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Aaron Ferguson
Music: Glass Boy / Nomad1
Intro voice: Jenny Schaye
Image: David J / Flickr // edit: Troy Farah

Episode 69: The Promise and Peril of the Psychedelic Mainstream with Shelby Hartman and Madison Margolin

March 21, 2022 Narcotica Episodes, Psychedelics 00:53:50 0 Comments

Psychedelics are not exactly taking the same path that cannabis has taken to the mainstream, but there are some similarities. In the late ‘90s and early aughts, when medical cannabis was first starting to take hold in California, quasi-legal businesses popped up overnight, with a lot of questionable quality control and these shops were often raided by the DEA. Now cannabis is so blasé in places like California and more than 15 other states that have adult-use weed, that it’s almost hard to imagine a time when you couldn’t have a bag of cannabis gummies, plus a joint dipped in oil and rolled in kief, delivered directly to your door like they used to do with Netflix DVDs.

Is that what we’re going to see with psilocybin, LSD, DMT and all the rest? Already people in some places like D.C., Colorado and Oregon are selling branded psychedelic edibles. In a lot of ways with psychedelics, we’re right where we were around 2010 with cannabis—a quasi-legal market that is ready to become legitimate, whether you like it or not.

Narcotica co-host Troy Farah talks with Shelby Hartman and Madison Margolin, two of the great minds behind DoubleBlind Magazine, a publication dedicated to all things psychedelics and much more in the periphery of psychedelic culture. They discuss some of the pros and cons psychedelics becoming mainstream, how people can navigate this emerging space, the Decriminalize Nature movement, reciprocity for Indigenous people and much more.

Visit https://doubleblindmag.com/ for more info.

Follow Madison on Twitter: @margolinmadison
Follow Shelby on Twitter: @shelbyannehart

If you liked this episode, here are others you might enjoy:
Episode 57: Autism, Acid and the Altered Brain with Aaron Orsini and Justine Lee
Episode 49: Salvia: Psychedelic Oddity with Ivan Casselman
Episode 59: Psychedelic Extinction—How Poaching Endangers Some Psychoactive Plants with Dr. Anya Ermakova

Follow Narcotica on Instagram, Facebook, Twitter, YouTube and support us on Patreon. Help keep this podcast ad-free! Your support is appreciated! We’re on Spotify, iTunes, Stitcher and more. Tell your friends about us! Rate us! And thanks for your support!

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah / Troy Farah
Music: Glass Boy / HoliznaCC0
Intro voice: Jenny Schaye
Image: Open Clipart // edit: Troy Farah

Episode 68: Is The Drug War Getting Better… Or Worse? with Zach Siegel, Chris Moraff and Troy Farah

March 3, 2022 Narcotica Episodes, Opioids, Overdose Crisis, Psychedelics 01:10:13 0 Comments

On this episode, Narcotica co-hosts Zachary Siegel, Chris Moraff and Troy Farah interview each other, riffing on one question: Is the drug war getting better… Or worse? They cover everything from nitazenes, Dopesick, the Drug User’s Liberation Front, banning psychedelics like DiPT, benzo dope, West Virginia, buprenorphine, psychedelic exceptionalism, drug testing, crack pipes, supervised consumption sites in NYC and much, much, more.

Their conclusion? You’ll have to listen to find out. OK, not really: Like many things, it’s a mix of both progress and backsliding. Narcotica’s founders discuss their current frustrations and what’s giving them optimism in America’s longest running war, a conflict directed at people. Maybe the end is in sight after all.

Follow Chris Moraff on Twitter: @moraffreports
Follow Zach Siegel on Twitter: @ZachWritesStuff
Follow Troy Farah on Twitter: @filth_filler

If you liked this episode, here are others you might enjoy:
Episode 27: What’s the Most Dangerous Drug?
Episode 58: How Racism Fuels The Drug War with Kassandra Frederique
Episode 51: The Joy of Drug Use with Dr. Carl Hart

Follow Narcotica on Instagram, Facebook, Twitter, YouTube and support us on Patreon. Help keep this podcast ad-free! Your support is appreciated! We’re on Spotify, iTunes, Stitcher and more. Tell your friends about us! Rate us! And thanks for your support!

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah / Troy Farah
Music: Glass Boy / Holly Mangler
Intro voice: Jenny Schaye
Image: Noun Project // edit: Troy Farah

Episode 64: LSD And Psilocybin For Physical Pain? with Greg McKee and Dr. Johannes Ramaekers

November 3, 2021 Narcotica Episodes, Psychedelics 01:20:18 1 Comment

These days, there isn’t an ailment some Silicon Valley-esque startup is trying to treat with psychedelics. Of course you have depression, anxiety, addiction, PTSD and fear of death for the terminally ill—there’s some good data for treating all of that—but some of the more obscure treatments include anorexia and eating disorders, sexual dysfunction, dementia, and even rare conditions like fragile X syndrome.

Psychedelics are amazing drugs, but they’re not a panacea. It’s not that this research isn’t worth investigating, but how do you determine what’s just hype and what the actual potential of psilocybin, LSD, DMT, etc. really is?

It may be wise to be skeptical of psychedelics being used to treat physical pain. Yet while the research is very young, there is some fascinating evidence that psychedelics may help with chronic pain, fibromyalgia, cluster headaches and even phantom limb pain. And what’s interesting is so many different research institutions and corporations are exploring this question. It’s not exactly a fringe topic and Narcotica co-host Troy Farah dives in with two conversations.

The first is an interview with Greg McKee, CEO of Tryp Therapeutics, a California-based startup that is exploring chronic pain relief using psilocybin and another, psilocybin-based drug with an undisclosed formulation that is obliquely called TRP-8803. The company has partnered with the University of Michigan and the University of Wisconsin-Madison to study how these drugs might treat fibromyalgia and Tryp has added leading psychedelic researcher Robin Carhart-Harris to its scientific advisory board, where he will play a “critical role” in clinical trial design.

The second interview is with Dr. Johannes Ramaekers of Maastricht University, who says he is developing another pain study to look at psychedelics and fibromyalgia. He was the lead author of a very interesting study published in 2020 in the Journal of Psychopharmacology that found that quote “low doses of LSD might constitute a novel pharmacological therapy.”

Read Troy’s article in Scientific American here: https://www.scientificamerican.com/article/can-psychedelic-drugs-treat-physical-pain/

Read Dr. Ramaekers’ pain and LSD study here: https://doi.org/10.1177%2F0269881120940937

Learn more about Tryp Therapeutics at https://tryptherapeutics.com/

If you liked this episode, here are others you might enjoy:
Episode 41: What Does It All Ketamine? with Dr. Erica Zelfand
Episode 49: Salvia: Psychedelic Oddity (Plus, Canada’s Emerging Psilocybin Scene)
Episode 25: Banning Kratom Will Escalate the Opioid Overdose Crisis with Walter Prozialeck

Follow Narcotica on Instagram, Facebook, Twitter, YouTube and support us on Patreon. Help keep this podcast ad-free! Your support is appreciated! We’re on Spotify, iTunes, Stitcher and more. Tell your friends about us! Rate us! And thanks for your support!

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah
Music: Glass Boy
Intro voice: Jenny Schaye
Image: PXFuel // The Noun Project // edit: Troy Farah