Episode 72: When The Trip Doesn’t End with Ed Prideaux

Psychedelics and other drugs can trigger a condition called Hallucinogen Persisting Perception Disorder, a terrible name for a real condition that we don’t have much data on and is poorly understood. But while it’s clear that psychedelics shouldn’t be illegal, it’s also clear we’re still learning about some of the risks. This fascinating and often distressing phenomenon deserves a closer look, but not everything about it is devastatingly tragic, either.

In this episode of Narcotica, co-host Troy Farah talks all about HPPD with Ed Prideaux, a master’s student in psychology at the University of East London with a background in journalism. Ed is currently focused on researching and addressing the problems, possibilities and questions raised by HPPD: a broad, under-researched and not entirely uncommon condition in which people experience sustained and distressing changes to their visual perception (among other effects) after psychedelic trips. Ed has lived with these visual effects for nearly seven years, and is affiliated with a nonprofit launched last year to promote harm reduction around HPPD called the Perception Restoration Foundation.

Follow Ed at
Visit the Perception Restoration Foundation at: Perception.Foundation

Some more info on perception as a hallucination:

Some of the studies mentioned in this episode:
The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act
Flashback phenomena after administration of LSD and psilocybin in controlled studies with healthy participants
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science

If you liked this episode, here are others you might enjoy:
Episode 57: Autism, Acid and the Altered Brain with Aaron Orsini and Justine Lee
Episode 64: LSD And Psilocybin For Physical Pain? with Greg McKee and Dr. Johannes Ramaekers
Episode 59: Psychedelic Extinction—How Poaching Endangers Some Psychoactive Plants with Dr. Anya Ermakova

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*Note: Troy says niacin is Vitamin C, it’s actually Vitamin B3. We regret the error.

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Aaron Ferguson
Music: Glass Boy / Nomad1
Intro voice: Jenny Schaye
Image: David J / Flickr // edit: Troy Farah

Episode 39: Pain Patients Are Still Fighting For Their Lives with Kate Nicholson

In 2016, the Centers for Disease Control and Prevention laid out guidelines for primary care doctors prescribing opioids to treat chronic pain. Essentially, these guidelines stated that opioids should not be the first line treatment for pain, and that other methods should be tried first. Which is perfectly sensible.

But when it came to dosing and duration, these guidelines — not laws — guidelines, started to become widely misinterpreted. We don’t need to get in the weeds of morphine milligram equivalents here, but what wound up happening across the country is that doctors, medical boards, and even legislators took the guidelines as black letter law. And clearly mistook the intended audience for the guidelines: primary care providers. Not pain management specialists, primary care providers. The one you might go see for a wellness check up or if you have strep throat.

Why is all this important? Aren’t prescription opioids, after all, the very substance that ignited a massive wave of overdose deaths across the country? It’s not so simple. Well intended efforts to reduce everyday people’s exposure to high doses and long durations of opioids started to hit the wrong target: patients with chronic, intractable, debilitating pain.

And we have an excellent guest, civil rights attorney, writer, and advocate, Kate Nicholson. Kate has been a critical asset for the pain community, who has been speaking up about how policy intended to help is actually causing more harm. She has consulted on several Democratic presidential candidates, including Bernie Sanders, Julian Castro and even Joe Biden.

Follow Kate Nicholson on Twitter @speakingabtpain

Follow Narcotica on Facebook, Twitter and support us on Patreon. Your support is appreciated! We’re on Spotify, iTunes, YouTube, Stitcher and more. Tell your friends about us!

Producers: Christopher Moraff, Troy Farah, Zachary Siegel 
Co-producer: Garrett Farah
Music: Glass Boy / Garrett Farah / A A Aalto
Photo: U.S. Air Force photo illustration/Tech. Sgt. Mark R. W. Orders-Woempner // Edit Troy Farah

Episode 36: Moral Hazards and Naloxone, A Toxicologist’s Perspective with Ryan Marino

An opioid overdose can be a terrifying experience. When too much of a  drug like heroin or fentanyl floods the brain, it can cause your  breathing to stop. Sometimes you wake up, sometimes you don’t. But  there’s a miraculous drug called naloxone or brand name Narcan that can  reverse an opioid overdose and save your life.  

Today’s guest is Ryan Marino, an emergency room physician and medical  toxicologist at Cleveland University Hospitals. We discuss moral  hazards about naloxone, one of the most important drugs on the planet,  but also buprenorphine, competitive antagonists for benzos and  stimulants, and dispelling drug myths on social media. 

How to Get Naloxone by Zachary Siegel in VICE

Also visit:

Follow Ryan on Twitter.

Follow Narcotica on Facebook, Twitter and support us on Patreon. Your support is appreciated! We’re on Spotify, iTunes, YouTube, Stitcher and more.
Tell your friends about us!

Producers: Christopher Moraff, Troy Farah, Zachary Siegel
Co-producer: Garrett Farah
Music: Glass Boy / Min Y Llan

Photo: Naloxone via Wikipedia / Edit Troy Farah